Key result
Left univentricular pacing in patients with severe congestive heart failure significantly improved NYHA class by 40% (P<0.0001) and 6-minute walk distance by 30% (P=0.01) at 12 months.
Why the study?
Does left univentricular pacing improve exercise tolerance and left ventricular function in patients with severe congestive heart failure, sinus rhythm, and left bundle-branch block?
Population
22 patients with severe congestive heart failure, NYHA class III or IV, sinus rhythm, left bundle-branch…
Comparison
Left univentricular pacing for 12 months vs Baseline values (no separate control group)
Design
Cohort
Follow-up
12 months
Authors
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Left univentricular pacing was associated with midterm gains in exercise tolerance and LV function in HF; leaves open equivalence to biventricular pacing in RCTs.
Observational (n=22)
Does left univentricular pacing improve exercise tolerance and left ventricular function in patients with severe congestive heart failure, sinus rhythm, and left bundle-branch block?
p-value: p=<0.0001
Left univentricular pacing provides significant midterm improvements in exercise tolerance and left ventricular function in patients with severe heart failure and left bundle-branch block.
Blanc et al. (2004) conducted an observational in Severe congestive heart failure (n=22). Left univentricular pacing vs. Baseline was evaluated on NYHA class (p=<0.0001). Left univentricular pacing in patients with severe congestive heart failure significantly improved NYHA class by 40% (P<0.0001) and 6-minute walk distance by 30% (P=0.01) at 12 months.
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