Key result
Preexisting coronary artery calcification was associated with an increased risk of developing hypertension compared to no calcification (adjusted HR 1.63; 95% CI 1.02-2.60; P=0.04).
Why the study?
Does preexisting coronary artery calcification predict the development of hypertension in normotensive subjects?
Population
483 normotensive subjects, mean age 54 years, 83% males, who underwent a baseline evaluation of their CAC…
Comparison
Presence of coronary artery calcification at… vs Absence of coronary artery calcification at…
Design
Cohort
Follow-up
mean 6.6 ± 3.2 years
Authors
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Preexisting CAC may flag higher incident HTN risk in normotensives; leaves open whether it refines prediction beyond standard factors.
Cohort (n=483)
Does preexisting coronary artery calcification predict the development of hypertension in normotensive subjects?
Hazard Ratio: 1.63 (95% CI 1.02–2.6)
Absolute Event Rate: 27% vs 17%
p-value: p=0.04
Preexisting coronary artery calcification is independently associated with the future development of hypertension in initially normotensive individuals.
Grossman et al. (2012) conducted a cohort in Hypertension (n=483). Coronary artery calcification vs. No coronary artery calcification was evaluated on Newly developed hypertension (HR 1.63, 95% CI 1.02-2.60, p=0.04). Preexisting coronary artery calcification was associated with an increased risk of developing hypertension compared to no calcification (adjusted HR 1.63; 95% CI 1.02-2.60; P=0.04).
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