Key result
Higher systolic and pulse pressures are linked to greater angiographic CAC severity in CAD.
Why the study?
Are systolic blood pressure and pulse pressure associated with the severity of coronary artery calcification in patients with CAD?
Population
877 patients with coronary artery disease (CAD) undergoing coronary angiography
Design
Cross-sectional
Authors
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Supports hypothesis linking higher SBP/PP to CAC severity in CAD; leaves open whether BP lowering alters progression or outcomes.
Observational (n=877)
Are systolic blood pressure and pulse pressure associated with the severity of coronary artery calcification in patients with CAD?
p-value: p=<0.001
Systolic blood pressure and pulse pressure are independently associated with the presence and severity of angiographically detected coronary artery calcification in patients with CAD.
Mayer et al. (2007) conducted an observational in Coronary artery disease (n=877). Systolic blood pressure and pulse pressure vs. Lower blood pressure levels was evaluated on Severity of coronary artery calcification (CAC) (p=<0.001). Higher systolic blood pressure and pulse pressure were independently associated with increased severity of angiographic coronary artery calcification in patients with coronary artery disease (P<0.001).
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