Key result
Increased brachial-ankle pulse wave velocity was independently associated with the presence of white matter hyperintensities (OR 1.12; 95% CI 1.02-1.23).
Why the study?
Is increased brachial-ankle pulse wave velocity associated with white matter hyperintensities in patients without a history of stroke?
Population
240 consecutive patients with no history of stroke
Design
Cross-sectional
Authors
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baPWV-WMH association warrants prospective validation; does not support routine arteriosclerosis screening to prevent WMHs.
Cross-Sectional (n=240)
Is increased brachial-ankle pulse wave velocity associated with white matter hyperintensities in patients without a history of stroke?
Odds Ratio: 1.12 (95% CI 1.02–1.23)
Increased brachial-ankle pulse wave velocity is independently associated with white matter hyperintensities, suggesting arterial stiffness may contribute to cerebral microvascular abnormalities.
Saji et al. (2011) conducted a cross-sectional in No history of stroke (n=240). Brachial-ankle pulse wave velocity (baPWV) was evaluated on White matter hyperintensities (WMHs) (OR 1.12, 95% CI 1.02-1.23). Increased brachial-ankle pulse wave velocity was independently associated with the presence of white matter hyperintensities (OR 1.12; 95% CI 1.02-1.23).
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