Key result
The Na-Ca exchanger is widely distributed throughout all membranes in contact with the extracellular space in rat and guinea pig heart cells, including the sarcolemma and T-tubules.
Population
Fixed, isolated heart cells from rat and guinea pig
Design
Preclinical
Authors
Loading...
Rodent myocyte data warrant no clinical NCX changes; leaves open human validation and functional modeling.
The Na-Ca exchanger is widely distributed over the cell surface in rat and guinea pig heart cells, providing insight into its role in cardiac function.
Kieval et al. (1992) studied this question. The Na-Ca exchanger is widely distributed throughout all membranes in contact with the extracellular space in rat and guinea pig heart cells, including the sarcolemma and T-tubules.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: