Microvesicles as Cell–Cell Messengers in Cardiovascular Diseases
Key result
Extracellular vesicles act as cell-cell messengers transferring biological information and play an active role in inflammatory cardiovascular diseases, including atherosclerosis and angiogenesis.
Design
Review
Authors
Discussion
Loading...
Member takes
Implication
Broadens view of intercellular signaling in cardiovascular disease; leaves open EV roles as biomarkers or targets.
PICO
P
Population
Cardiovascular Diseases
E
Exposure / Comparator
Extracellular vesicles
Extracellular vesicles are emerging as important mediators of cell-cell communication and potential biomarkers in cardiovascular diseases.
Limitations
- The cellular machinery controlling their formation and composition, as well as the mechanisms regulating their extracellular release, remain much unknown.
Cite This Study
Loyer et al. (2014) conducted a review in Cardiovascular Diseases. Extracellular vesicles was evaluated. Extracellular vesicles act as cell-cell messengers transferring biological information and play an active role in inflammatory cardiovascular diseases, including atherosclerosis and angiogenesis.