Key result
Physical activity, exercise training, and cardiorespiratory fitness are associated with marked reductions in cardiovascular disease and alter the relationship between adiposity and major CVD outcomes.
Why the study?
Do physical activity, exercise training, and cardiorespiratory fitness improve cardiovascular outcomes in individuals with obesity?
Do physical activity, exercise training, and cardiorespiratory fitness improve cardiovascular outcomes in individuals with obesity?
Physical activity and cardiorespiratory fitness significantly reduce cardiovascular risk and modify the impact of obesity on cardiovascular outcomes.
CRF may refine CV risk evaluation in obesity; leaves open whether ET reduces HF and CHD incidence.
Obesity is associated with increased prevalence of cardiovascular (CV) disease (CVD) risk factors, which may adversely impact CV structure and function and may increase the prevalence of most CVD, particularly heart failure (HF) and coronary heart disease (CHD). Physical activity (PA), exercise training (ET) and cardiorespiratory fitness (CRF) are all associated with marked reductions in most CVD, including HF and CHD. Additionally, PA/ET and, especially CRF, markedly alter the relationship between adiposity and subsequent major CVD outcomes and dramatically impact the "obesity paradox," which are all reviewed, including attention to the debate regarding "fitness versus fatness" for long-term prognosis, including in patients with established CVD.
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Lavie et al. (2019) conducted a review in Obesity and cardiovascular disease. Physical activity, exercise training, and cardiorespiratory fitness was evaluated. Physical activity, exercise training, and cardiorespiratory fitness are associated with marked reductions in cardiovascular disease and alter the relationship between adiposity and major CVD outcomes.
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