Key result
Optical measurement determined the average molar absorption coefficient of HbA1c to be 804,403.5 M−1cm−1 at 545 nm and 703,704.5 M−1cm−1 at 579 nm for level 1.
Why the study?
The molar absorption coefficient of HbA1c is needed to quantify HbA1c present in a blood sample for timely diabetes diagnosis.
Population
Level 1 and level 2 HbA1c samples
Design
Experimental optical measurement study
Authors
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Measured HbA1c absorption coefficients support optical quantification; leaves open clinical validation before diagnostic use.
This study provides experimental measurements of the molar absorption coefficient of HbA1c in the visible wavelength region, which may aid future development of noninvasive HbA1c estimation methods.
Hossain et al. (2022) studied Diabetes. Optical measurement of molar absorption coefficient was evaluated on Molar absorption coefficient of HbA1c in the range of 450 nm to 700 nm. Optical measurement determined the average molar absorption coefficient of HbA1c to be 804,403.5 M−1cm−1 at 545 nm and 703,704.5 M−1cm−1 at 579 nm for level 1.
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