Key result
Fetuses with coarctation of the aorta exhibited significantly decreased aortic strain of the ascending aorta compared to normal fetuses (18.12% vs. 25.22%, p<0.01).
Why the study?
To observe the elasticity of the ascending aorta in normal fetuses and fetuses with aortic coarctation using M-mode echocardiography.
Does aortic coarctation reduce ascending aorta elasticity and alter cardiac function in fetuses?
Observational (n=64)
No
Does aortic coarctation reduce ascending aorta elasticity and alter cardiac function in fetuses?
Absolute Event Rate: 18.12% vs 25.22%
p-value: p=<0.01
Fetuses with aortic coarctation exhibit significantly decreased ascending aorta elasticity in utero, which correlates with impaired left ventricular function.
No takes yet. Share an insight, caveat, or question.
Reduced AAo strain in CoA fetuses may signal altered elasticity; leaves open diagnostic utility pending larger validation studies.
Zhou et al. (2022) conducted an observational in Coarctation of the aorta (n=64). Coarctation of the aorta vs. Normal fetuses was evaluated on Aortic strain of the ascending aorta (p=<0.01). Fetuses with coarctation of the aorta exhibited significantly decreased aortic strain of the ascending aorta compared to normal fetuses (18.12% vs. 25.22%, p<0.01).
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: