Key result
Spontaneous and induced locomotion in decerebrate cats was associated with an immediate increase in ventilation, smaller tidal volume, and larger respiratory rate compared to rest.
Population
High decerebrate unanaesthetized cats (pre-collicular/pre-mamillary)
Comparison
Spontaneous locomotion and locomotion induced by… vs Rest (cessation of locomotion)
Design
Preclinical
Authors
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Locomotor-respiratory coupling observed in cats; leaves open translation to human exercise hyperpnea.
The virtually simultaneous changes in quadriceps activity and respiratory motor activities suggest that the increase in ventilation at exercise onset is neurally mediated.
DiMarco et al. (1983) studied this question. Locomotion (spontaneous or induced) vs. Rest was evaluated on Ventilation and respiratory pattern changes. Spontaneous and induced locomotion in decerebrate cats was associated with an immediate increase in ventilation, smaller tidal volume, and larger respiratory rate compared to rest.
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