Key result
Low plasma extracellular superoxide dismutase levels were independently associated with an increased likelihood of a history of myocardial infarction (OR 2.04; 95% CI 1.10-3.82).
Population
590 white Australian patients ≤65 years old with angiographically documented coronary artery disease
Design
Cross-sectional
Authors
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Low EC-SOD may flag prior MI risk; hypothesis-generating for protective CAD role, needing prospective confirmation before practice change.
Cross-Sectional (n=590)
Odds Ratio: 2.04 (95% CI 1.1–3.82)
Lower circulating EC-SOD levels are independently associated with a history of myocardial infarction, suggesting a potential protective role against coronary risk.
Wang et al. (1998) conducted a cross-sectional in Coronary artery disease (n=590). Low plasma extracellular superoxide dismutase (EC-SOD) levels vs. Higher plasma EC-SOD levels was evaluated on History of acute myocardial infarction (MI) (OR 2.04, 95% CI 1.10 to 3.82). Low plasma extracellular superoxide dismutase levels were independently associated with an increased likelihood of a history of myocardial infarction (OR 2.04; 95% CI 1.10-3.82).
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