July 1, 1997Journal of Internal Medicine
Two variants of extracellular‐superoxide dismutase: relationship to cardiovascular risk factors in an unselected middle‐aged population
Population
4,900 randomly selected subjects aged 25-74 years from the general population in Norrbotten and Västerbotten…
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
The variant's observational ties to risk factors should not change practice; leaves open independent effects on cardiovascular outcomes.
Structured PICO
P
Population
4,900 randomly selected subjects aged 25-74 years from the general population in Norrbotten and Västerbotten counties in northern Sweden.
O
Outcome
Plasma levels of extracellular-superoxide dismutase (EC-SOD)surrogate
A genetic variant causing high plasma levels of EC-SOD is present in approximately 4% of the Swedish population and correlates with several conventional cardiovascular risk factors.
Cite This Study
Marklund et al. (1997) studied this question.