Key result
Working 10 hours per day or more was associated with a lower risk of developing hypertension (HR 0.58; 95% CI 0.41-0.82), an effect likely mediated indirectly through less overall obesity.
Why the study?
Do lifestyle factors such as alcohol intake, BMI, and working hours predict the development of hypertension in middle-aged Japanese male office workers?
Cohort (n=949)
Do lifestyle factors such as alcohol intake, BMI, and working hours predict the development of hypertension in middle-aged Japanese male office workers?
Hazard Ratio: 0.58 (95% CI 0.41–0.82)
Higher BMI and daily alcohol intake independently increase the risk of developing hypertension, while longer working hours appear protective, likely mediated indirectly through lower overall obesity.
No takes yet. Share an insight, caveat, or question.
Should not change work-hour advice; hypothesis-generating in Japanese men and requires confirmation before broader inference.
Nakanishi et al. (1999) conducted a cohort in Hypertension (n=949). Working 10 hours per day or more vs. Working less than 10 hours per day was evaluated on Development of hypertension (blood pressure ≥ 140/90 mmHg) (HR 0.58, 95% CI 0.41-0.82). Working 10 hours per day or more was associated with a lower risk of developing hypertension (HR 0.58; 95% CI 0.41-0.82), an effect likely mediated indirectly through less overall obesity.
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