What question did this study set out to answer?

Evaluate the effectiveness of intravenous clonidine compared to fentanyl in attenuating hemodynamic responses during intubation.

August 1, 2026

Comparative study of intravenous clonidine versus fentanyl in attenuating hemodynamic response to laryngoscopy and tracheal intubation

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Evaluate the effectiveness of intravenous clonidine compared to fentanyl in attenuating hemodynamic responses during intubation.
Prospective, randomized study involving 80 adult patients scheduled for elective surgeries.
Patients received either IV clonidine (4 μg/kg) or IV fentanyl (2 μg/kg) five minutes before intubation.
Hemodynamic parameters were recorded at several time points before and after intubation.
Systolic blood pressure was significantly lower in the fentanyl group at 5-min post-intubation (P=0.037).
Inter-group differences in diastolic blood pressure, mean arterial pressure, heart rate, and oxygen saturation were not statistically significant.
Intra-group analysis showed transient fluctuations in systolic, diastolic blood pressure, and mean arterial pressure after intubation.

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Implication

Randomized trial compares hemodynamic responses to laryngoscopy and intubation in adults using clonidine and fentanyl, indicating both are effective but vary by patient profile.

Cite This Study

Tiwari et al. (2026) studied this question.

synapsesocial.com/papers/6a6d97eae258b358b3c6ab04 https://doi.org/10.71152/ajms.v17i8.5400

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Implication

Randomized trial compares hemodynamic responses to laryngoscopy and intubation in adults using clonidine and fentanyl, indicating both are effective but vary by patient profile.

Comparative study of intravenous clonidine versus fentanyl in attenuating hemodynamic response to laryngoscopy and tracheal intubation

Key Points

Discussion

Implication

Cite This Study

Comparative study of intravenous clonidine versus fentanyl in attenuating hemodynamic response to laryngoscopy and tracheal intubation

Key Points

Discussion

Implication

Cite This Study

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