Why the study?
Does intravenous low dose clonidine premedication attenuate hemodynamic responses to laryngoscopy and endotracheal intubation in patients undergoing elective non-cardiovascular surgeries?
Population
60 patients (30 per group) presenting for elective, non-cardiovascular surgeries
Comparison
Intravenous clonidine 1.5 µg/kg as a single… vs Normal saline (placebo)
Design
Cohort
Follow-up
10 minutes post-intubation
Authors
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May support low-dose clonidine to blunt intubation responses in elective surgery; leaves open randomized confirmation before practice change.
Does intravenous low dose clonidine premedication attenuate hemodynamic responses to laryngoscopy and endotracheal intubation in patients undergoing elective non-cardiovascular surgeries?
Low-dose intravenous clonidine premedication effectively blunts the sympathetic hemodynamic response to laryngoscopy and intubation in non-cardiovascular surgeries.
Kavi et al. (2015) studied this question.
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