Why the study?
Does oral clonidine premedication attenuate the hemodynamic stress response to laryngoscopy and intubation in patients undergoing elective surgeries under general anesthesia?
Population
n=50 patients of either sex, aged 20-60 years, ASA grade I/II undergoing elective surgeries under general…
Comparison
Clonidine 3 mcg/kg orally 90 min before induction vs 5 ml distilled water
Design
RCT, randomized, double-blind
Follow-up
5 minutes following intubation
Authors
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Supports oral clonidine premedication to blunt intubation hemodynamics; confirms efficacy in elective general anesthesia.
Does oral clonidine premedication attenuate the hemodynamic stress response to laryngoscopy and intubation in patients undergoing elective surgeries under general anesthesia?
Oral clonidine 3 mcg/kg given 90 minutes before induction effectively attenuates the hemodynamic stress response to laryngoscopy and intubation.
Rani et al. (2015) studied this question.
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