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Clonidine route comparison for intubation hemodynamics remains inconclusive; leaves open optimal dosing and administration in anesthesia practice.
Background And Objectives: Laryngoscopy with or without tracheal intubation amounts to a highly noxious stimulus to the homeostasis of the patient. Many a times under lighter planes of anaesthesia it elicits a defence mechanism in the form of haemodynamic response to stress, which involves activation of adrenocortical system. This study was conducted to compare the effects of oral Clonidine and IV Clonidine premedication on haemodynamic response to laryngoscopy and endotracheal intubation.
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A 2013 study studied this question.
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