Key result
Overweight and obese subjects had significantly higher arterial stiffness and lower plasma PTX3 concentrations than normal-weight subjects, though multivariable analysis showed no association.
Why the study?
Is there an association between plasma PTX3 levels and arterial stiffness in overweight and obese individuals?
Population
282 subjects classified as normal weight, overweight, or obese based on body mass index
Design
Cross-sectional
Authors
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No independent PTX3-stiffness link after adjustment in obesity; leaves open any causal role.
Cross-Sectional (n=282)
Is there an association between plasma PTX3 levels and arterial stiffness in overweight and obese individuals?
Increased arterial stiffness in overweight and obese individuals may be partly associated with reduced plasma PTX3 concentrations, although multivariable analysis did not confirm an independent association.
Miyaki et al. (2013) conducted a cross-sectional in Overweight and obesity (n=282). Overweight and obesity vs. Normal weight was evaluated on Arterial stiffness (baPWV and cfPWV) and plasma PTX3 concentrations. Overweight and obese subjects had significantly higher arterial stiffness and lower plasma PTX3 concentrations than normal-weight subjects, though multivariable analysis showed no association.
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