Key result
Healthy male carriers of the CD300LG rs72836561 polymorphism had higher intramyocellular lipid content (P=0.045) and reduced fasting forearm glucose uptake (P=0.011) compared to controls.
Why the study?
Does the CD300LG rs72836561 polymorphism affect lipid accumulation and glucose metabolism in healthy men?
Population
40 healthy men, mean age 55 years
Comparison
CD300LG rs72836561 CT genotype vs CD300LG rs72836561 CC genotype (controls)
Design
Cross-sectional
Authors
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Should not change practice; leaves open CD300LG as a candidate gene in metabolic syndrome.
Cross-Sectional (n=40)
Does the CD300LG rs72836561 polymorphism affect lipid accumulation and glucose metabolism in healthy men?
p-value: p=0.045
Støy et al. (2015) conducted a cross-sectional in Healthy (n=40). CD300LG rs72836561 polymorphism (CT carriers) vs. CC carriers (controls) was evaluated on Intramyocellular lipid content (IMCL) (p=0.045). Healthy male carriers of the CD300LG rs72836561 polymorphism had higher intramyocellular lipid content (P=0.045) and reduced fasting forearm glucose uptake (P=0.011) compared to controls.
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