Key result
Interleukin-6 plays a central role in the pathophysiology of various cardiovascular diseases, including heart failure and myocarditis, though its ultimate beneficial or detrimental effects remain to be fully determined.
Design
Review
Authors
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IL-6 elevation may mark worsening LV dysfunction; leaves open whether targeting it alters heart failure outcomes.
This review highlights the pleiotropic role of interleukin-6 in the pathophysiology of various cardiovascular diseases, including heart failure, myocarditis, and coronary artery disease, though its ultimate beneficial or detrimental nature remains to be fully elucidated.
Kanda et al. (2004) conducted a review in Cardiovascular Diseases. Interleukin-6 was evaluated. Interleukin-6 plays a central role in the pathophysiology of various cardiovascular diseases, including heart failure and myocarditis, though its ultimate beneficial or detrimental effects remain to be fully determined.
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