Key result
Newly diagnosed abnormal glucose tolerance in patients with acute myocardial infarction significantly increased the risk of future cardiovascular events compared to normal glucose tolerance (HR 2.65).
Why the study?
Does newly diagnosed abnormal glucose tolerance increase the risk of cardiovascular events in patients with acute myocardial infarction?
Population
275 prospectively enrolled patients with acute myocardial infarction (AMI)
Comparison
Newly diagnosed abnormal glucose tolerance or… vs Normal glucose tolerance
Design
Cohort
Follow-up
median 5.3 years
Authors
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Abnormal glucose tolerance post-AMI flags higher-risk patients; leaves open whether targeted intervention improves long-term outcomes.
Cohort (n=275)
No
Does newly diagnosed abnormal glucose tolerance increase the risk of cardiovascular events in patients with acute myocardial infarction?
Hazard Ratio: 2.65 (95% CI 1.37–5.15)
Absolute Event Rate: 30% vs 13%
p-value: p=0.004
Newly diagnosed abnormal glucose tolerance in AMI patients is a major risk factor for future cardiovascular events, conferring a prognosis similar to that of pre-existing diabetes.
Tamita et al. (2007) conducted a cohort in Acute Myocardial Infarction (n=275). Abnormal glucose tolerance vs. Normal glucose tolerance was evaluated on Major adverse cardiovascular events (MACE) (HR 2.65, 95% CI 1.37-5.15, p=0.004). Newly diagnosed abnormal glucose tolerance in patients with acute myocardial infarction significantly increased the risk of future cardiovascular events compared to normal glucose tolerance (HR 2.65).
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