Key result
Numerical modeling of transcatheter heart valves demonstrated that crimping stresses are inevitable and particularly critical on the leaflets at the suture sites connected with the skirt.
Why the study?
Very few numerical investigations have evaluated the effects of leaflet curvature and thickness on crimping stresses arising during surgical preparation processes of transcatheter heart valves.
Computational modeling demonstrates that crimping of transcatheter heart valves generates critical stresses at leaflet suture sites, potentially impacting valve durability and causing ruptures.
Supports caution on crimping stresses at leaflet sutures; hypothesis-generating for THV design refinements to improve durability.
With the current advances and expertise in biomedical device technologies, transcatheter heart valves (THVs) have been drawing significant attention. Various studies have been carried out on their durability and damage by dynamic loading in operational conditions. However, very few numerical investigations have been conducted to understand the effects of leaflet curvature and thickness on the crimping stresses which arise during the surgical preparation processes. In order to contribute to the current state of the art, a full heart valve model was presented, the leaflet curvature and thickness of which were then parameterized so as to understand the stress generation as a result of the crimping procedure during the surgical preparations. The results show that the existence of stresses is inevitable during the crimping procedure, which is a reduction factor for valve durability. Especially, stresses on the leaflets at the suture sites connected with the skirt were deduced to be critical and may result in leaflet ruptures after THV implantation.
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Karakoç et al. (2023) studied Transcatheter heart valve crimping stresses. Leaflet curvature and thickness was evaluated on Crimping stresses. Numerical modeling of transcatheter heart valves demonstrated that crimping stresses are inevitable and particularly critical on the leaflets at the suture sites connected with the skirt.
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