Key result
The incidence of hyperosmolar hyperglycemic state was 16.5 per 10,000 person-years among patients with type 1 diabetes compared with 3.9 per 10,000 person-years among those with type 2 diabetes.
Why the study?
The hyperosmolar hyperglycemic state is a rare and life-threatening complication of diabetes, but its incidence and clinical and biomarker profiles remained to be estimated and described.
Population
634 acutely admitted patients fulfilling criteria of HHS among 4.80 million inhabitants aged ≥18 years in Denmark
Design
Nationwide descriptive cohort study
Authors
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Elevated HHS incidence in type 1 versus type 2 diabetes supports risk awareness; leaves open whether it should guide targeted prevention.
Cohort (n=634)
Yes
Absolute Event Rate: 16.5% vs 3.9%
Rosager et al. (2023) conducted a cohort in Hyperosmolar hyperglycemic state (n=634). Type 1 diabetes vs. Type 2 diabetes was evaluated on Incidence of HHS (per 10,000 person-years). The incidence of hyperosmolar hyperglycemic state was 16.5 per 10,000 person-years among patients with type 1 diabetes compared with 3.9 per 10,000 person-years among those with type 2 diabetes.
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