Key result
A proposed mathematical model of constitutive relations for active fiber stress in cardiac muscle successfully fit experimental data and predicted end-systolic transmural strain distributions.
Population
Computational model of cardiac muscle contraction based on experimental data from the literature
Design
Preclinical
Authors
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Model fits animal data for active fiber stress; leaves open human validation and clinical translation.
The study proposes a mathematical model for active fiber stress in cardiac muscle that accurately describes deactivation and fits experimental data.
Guccione et al. (1993) studied Cardiac muscle contraction. A proposed mathematical model of constitutive relations for active fiber stress in cardiac muscle successfully fit experimental data and predicted end-systolic transmural strain distributions.
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