Key result
TMEV induces persistent infection of oligodendrocytes in SJL/J mice up to 360 days postinfection, potentially serving as a target for immune-mediated demyelination.
Authors
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TMEV antigen shifts to oligodendrocytes late in infection; leaves open mechanistic parallels in human progressive demyelination.
Rodriguez et al. (1983) studied Theiler's murine encephalomyelitis virus (TMEV) infection. Theiler's murine encephalomyelitis virus (TMEV) infection was evaluated on Localization of viral antigen in infected cells of the spinal cord. TMEV induces persistent infection of oligodendrocytes in SJL/J mice up to 360 days postinfection, potentially serving as a target for immune-mediated demyelination.
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