Why the study?
Does oxyfedrine improve regional myocardial blood flow and segmental wall function in a porcine model of myocardial ischemia?
Population
17 pigs with myocardial ischemia induced by reducing left anterior descending coronary artery flow to…
Comparison
Oxyfedrine administered after 10 min of flow… vs Control group with induced ischemia not…
Design
Preclinical
Follow-up
Acute
Authors
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Preclinical porcine data only; leaves open any clinical translation of oxyfedrine for myocardial ischemia.
Does oxyfedrine improve regional myocardial blood flow and segmental wall function in a porcine model of myocardial ischemia?
In a porcine model of myocardial ischemia, oxyfedrine administration increases blood flow to ischemic myocardium and improves systolic wall thickening.
SCHAMHARDT et al. (1980) studied this question.
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