Key result
Interatrial septum pacing decreased pacing P wave duration (95 vs 138; P=0.001) and atrial contraction delay compared to right atrial appendage pacing, but did not reduce AF incidence.
Why the study?
Does interatrial septum pacing decrease atrial contraction delay and prevent atrial fibrillation progression compared to right atrial appendage pacing in patients with sinus node disease?
Cohort (n=52)
Does interatrial septum pacing decrease atrial contraction delay and prevent atrial fibrillation progression compared to right atrial appendage pacing in patients with sinus node disease?
Absolute Event Rate: 95% vs 138%
p-value: p=0.001
Interatrial septum pacing decreases atrial contraction delay compared to right atrial appendage pacing, but this does not translate to a reduction in the progression of paroxysmal to permanent atrial fibrillation.
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Interatrial septum pacing was associated with better atrial synchrony but not lower AF; leaves open whether pacing site affects AF progression in sinus node disease.
Yasuoka et al. (2010) conducted a cohort in Sinus node disease (n=52). Interatrial septum pacing (IAS-P) vs. Right atrial appendage pacing (RAA-P) was evaluated on Pacing P wave duration (p=0.001). Interatrial septum pacing decreased pacing P wave duration (95 vs 138; P=0.001) and atrial contraction delay compared to right atrial appendage pacing, but did not reduce AF incidence.
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