Population
Porcine coronary artery in vitro (endothelium-intact and -denuded rings)
Comparison
Adenosine analogues vs Presence vs absence of endothelium; presence vs…
Design
Preclinical
Authors
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Caution against clinical extrapolation from porcine data; leaves open selective A2 agonism for targeted coronary research.
This preclinical study demonstrates that multiple A2-adenosine receptors exist on the smooth muscle and endothelium of porcine coronary arteries, mediating relaxation.
Abebe et al. (1994) studied this question.
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