Why the study?
Do thyroid hormones (T3 and T4) have direct vasodilatory effects on rat skeletal muscle resistance arteries?
Population
Rat skeletal muscle resistance arteries of approximately 100 microns
Comparison
Triiodothyronine or levothyroxine at increasing… vs Preconstricted vessels without thyroid hormone…
Design
Preclinical
Authors
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Supports direct vasodilatory effects of T3/T4 on rat resistance arteries; leaves open applicability to human cardiovascular physiology.
Do thyroid hormones (T3 and T4) have direct vasodilatory effects on rat skeletal muscle resistance arteries?
Thyroid hormones (T3 and T4) possess direct, concentration-dependent vasodilatory effects on skeletal muscle resistance arteries, mediated by both endothelium-dependent and independent mechanisms.
Park et al. (1997) studied this question.
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