Population
Washed human platelets
Comparison
ADP, epinephrine, and collagen in dialysed plasma vs Washed platelets in buffered solution; presence…
Design
Preclinical
Authors
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Supports thrombin's role in platelet responses; hypothesis-generating from animal data and leaves open human translation.
The study provides evidence that thrombin plays a central role in the platelet release reaction and biphasic aggregation caused by various agents, and that citrate effects are due to cation concentration reduction.
Huzoor‐Akbar et al. (1978) studied this question.
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