What question did this study set out to answer?

This study aims to evaluate the effects of balloon valvuloplasty on left ventricular and valve function in patients with critical aortic stenosis.

January 1, 1987CirculationOpen Access

Assessment of left ventricular and aortic valve function after aortic balloon valvuloplasty in adult patients with critical aortic stenosis.

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Why the study?

Does aortic balloon valvuloplasty improve left ventricular and valvular function in adult patients with critical aortic stenosis?

Population

32 adult patients (mean age 79 years) with long-standing, calcific critical aortic stenosis.

Design

Case_series

Authors

RMRaymond G. McKayInterventional Cardiology RSRobert D. SafianInterventional Cardiology JLJames E. LockPediatric Cardiology

Discussion

Member takes

Implication

May acutely improve hemodynamics in critical AS; hypothesis-generating, with durability and role versus replacement unproven.

Key Points

This study aims to evaluate the effects of balloon valvuloplasty on left ventricular and valve function in patients with critical aortic stenosis.
32 adults with critical aortic stenosis treated with balloon valvuloplasty during cardiac catheterization.
Assessment of cardiac performance using radionuclide ventriculography, Doppler echocardiography, and systolic time interval measures before and after the procedure.
Measurements included aortic valve gradient, cardiac output, and aortic valve area.
Aortic valve gradient reduced from 77 +/- 27 mm Hg to 39 +/- 15 mm Hg post-valvuloplasty (p<.001).
Cardiac output increased from 4.6 +/- 1.4 liters/min to 5.2 +/- 1.8 liters/min (p<.03).
Left ventricular ejection fraction improved from 40 +/- 13% to 46 +/- 12% (p<.03).

Structured PICO

Does aortic balloon valvuloplasty improve left ventricular and valvular function in adult patients with critical aortic stenosis?

Population

32 adult patients (mean age 79 years) with long-standing, calcific critical aortic stenosis.

Intervention

Aortic balloon valvuloplasty (balloon dilatation of the aortic valve with 12 to 23 mm balloons) at the time of cardiac catheterization.

Outcome

Serial changes in left ventricular and valvular function measured by radionuclide ventriculography, systolic time intervals, and Doppler echocardiography.surrogate

Aortic balloon valvuloplasty in high-risk patients with critical aortic stenosis acutely improves aortic valve area, transvalvular gradient, and left ventricular performance.

Cite This Study

McKay et al. (1987) studied this question.

synapsesocial.com/papers/6a6f4abfac440176ef27fe80 https://doi.org/10.1161/01.cir.75.1.192

Topics

Echocardiography

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Assessment of left ventricular and aortic valve function after aortic balloon valvuloplasty in adult patients with critical aortic stenosis.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Assessment of left ventricular and aortic valve function after aortic balloon valvuloplasty in adult patients with critical aortic stenosis.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

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