Key result
Percutaneous aortic balloon valvuloplasty reduces transvalvular gradient ~41% but carries high immediate risk and medium-term restenosis.
Why the study?
Does percutaneous aortic balloon valvuloplasty improve hemodynamics and symptoms in elderly patients with calcific aortic stenosis who are poor surgical candidates?
Population
25 elderly patients with calcific aortic stenosis, mean age 74.8 +/- 7.6 years, 48% male, 52% female…
Design
Case_series
Follow-up
mean 13.0 +/- 5.0 months
Authors
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High procedural risks and restenosis caution palliative use in inoperable elderly AS; leaves open role versus modern transcatheter options.
Observational (n=25)
Does percutaneous aortic balloon valvuloplasty improve hemodynamics and symptoms in elderly patients with calcific aortic stenosis who are poor surgical candidates?
Absolute Event Rate: 43% vs 73%
p-value: p=<0.000001
Percutaneous aortic balloon valvuloplasty provides palliative hemodynamic and functional improvement in elderly patients with calcific aortic stenosis who are poor surgical candidates, though it carries significant procedural risks and restenosis rates.
Serruys et al. (1988) conducted an observational in Calcific aortic stenosis (n=25). Percutaneous aortic balloon valvuloplasty was evaluated on Mean systolic aortic transvalvular gradient (p=<0.000001). Percutaneous aortic balloon valvuloplasty reduced the mean systolic aortic transvalvular gradient from 73 to 43 mmHg (P<0.000001), but carried high immediate risks and medium-term restenosis.
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