What question did this study set out to answer?

To evaluate the feasibility, safety, and short-term hemodynamic and clinical outcomes of percutaneous balloon aortic valvuloplasty in elderly patients with severe calcific aortic stenosis at high risk for surgery.

May 1, 1987Annals of Internal Medicine

Percutaneous Balloon Aortic Valvuloplasty for Aortic Stenosis in Elderly Patients at High Risk for Surgery

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Why the study?

Does percutaneous balloon aortic valvuloplasty improve hemodynamics and symptoms in elderly patients with severe, symptomatic calcific aortic stenosis at high risk for surgery?

Population

n=6 elderly patients with severe, symptomatic calcific aortic stenosis at high risk for surgery

Design

Case_series

Follow-up

mean 2 months

Authors

JSJohn F. SchneiderThe University of Texas at San Antonio

Discussion

Member takes

Implication

May offer short-term hemodynamic relief in high-risk elderly AS; leaves open durability and comparative efficacy.

Key Points

To evaluate the feasibility, safety, and short-term hemodynamic and clinical outcomes of percutaneous balloon aortic valvuloplasty in elderly patients with severe calcific aortic stenosis at high risk for surgery.
Interventional study in N=6 elderly patients with severe, symptomatic calcific aortic stenosis deemed high risk for surgical valve replacement (n=5) or refusing surgery (n=1).
Patients underwent percutaneous balloon aortic valvuloplasty via femoral puncture, with hemodynamic measurements and a mean follow-up of 2 months.
Mean aortic valve gradient decreased from 47 ± 13 to 32 ± 12 mm Hg (-32%, p < 0.01), and mean aortic valve area increased from 0.64 ± 0.12 to 0.90 ± 0.17 cm² (+40%, p < 0.001).
At 2-month follow-up, all 6 patients survived, with dyspnea improving by two NYHA functional classes in 4 patients and by one class in 2 patients; femoral puncture bleeding was the only major complication.

Structured PICO

Does percutaneous balloon aortic valvuloplasty improve hemodynamics and symptoms in elderly patients with severe, symptomatic calcific aortic stenosis at high risk for surgery?

Population

n=6 elderly patients with severe, symptomatic calcific aortic stenosis at high risk for surgery (5 due to severe coexisting cardiac or other medical problems, 1 refused surgery)

Intervention

Percutaneous balloon aortic valvuloplasty

Outcome

Change in mean aortic valve gradient and mean area of the aortic valvesurrogate

Percutaneous balloon aortic valvuloplasty safely provides short-term hemodynamic and symptomatic improvement in elderly patients with severe aortic stenosis who are poor surgical candidates.

Cite This Study

John F. Schneider (1987) studied this question.

synapsesocial.com/papers/6a8c6c95cce18bb2086c15bb https://doi.org/10.7326/0003-4819-106-5-696

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Percutaneous Balloon Aortic Valvuloplasty for Aortic Stenosis in Elderly Patients at High Risk for Surgery

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Percutaneous Balloon Aortic Valvuloplasty for Aortic Stenosis in Elderly Patients at High Risk for Surgery

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Also Consider