Key result
Systemic lupus erythematosus was associated with significantly impaired left ventricular longitudinal function, including reduced global strain (-15.11% vs -19.7%), in asymptomatic patients.
Why the study?
Do tissue Doppler and strain imaging detect subclinical left ventricular dysfunction in asymptomatic patients with systemic lupus erythematosus compared to healthy controls?
Population
107 subjects total: 67 young patients with Systemic Lupus Erythematosus without typical symptoms or signs of…
Design
Case-control, Analyses of the echocardiographic examinations were performed by…
Authors
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May support strain imaging for subclinical LV detection in asymptomatic SLE; leaves open prognostic value and management implications.
Case-Control (n=107)
Single-blind
No
Do tissue Doppler and strain imaging detect subclinical left ventricular dysfunction in asymptomatic patients with systemic lupus erythematosus compared to healthy controls?
Absolute Event Rate: -15.11% vs -19.7%
p-value: p=<0.05
Tissue Doppler and strain imaging can detect subclinical left ventricular systolic and diastolic dysfunction in asymptomatic patients with systemic lupus erythematosus who have normal standard echocardiograms.
Buss et al. (2009) conducted a case-control in Systemic lupus erythematosus (n=107). Systemic lupus erythematosus vs. Healthy controls was evaluated on Global strain (SR) (p=<0.05). Systemic lupus erythematosus was associated with significantly impaired left ventricular longitudinal function, including reduced global strain (-15.11% vs -19.7%), in asymptomatic patients.
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