Key result
Systemic lupus erythematosus patients had significantly worse left ventricular global longitudinal strain compared to healthy controls (-18.56% vs. -19.89%; P=0.028).
Why the study?
Does two-dimensional speckle-tracking echocardiography detect subclinical ventricular systolic dysfunction in asymptomatic patients with systemic lupus erythematosus compared to healthy controls?
Population
70 subjects: 45 patients with systemic lupus erythematosus and 25 healthy controls, matched for age and sex…
Comparison
Echocardiography including tissue Doppler… vs Healthy controls matched for age and sex
Design
Case-control
Authors
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Speckle-tracking echocardiography may detect subclinical LV dysfunction in asymptomatic SLE; hypothesis-generating and requires prospective validation before clinical use.
Case-Control (n=70)
Does two-dimensional speckle-tracking echocardiography detect subclinical ventricular systolic dysfunction in asymptomatic patients with systemic lupus erythematosus compared to healthy controls?
Absolute Event Rate: -18.56% vs -19.89%
p-value: p=0.028
Two-dimensional speckle-tracking echocardiography can detect subclinical left ventricular systolic dysfunction in asymptomatic patients with systemic lupus erythematosus independent of traditional risk factors.
Poorzand et al. (2015) conducted a case-control in Systemic lupus erythematosus (n=70). Systemic lupus erythematosus vs. Healthy controls was evaluated on Left ventricular global longitudinal systolic strain (p=0.028). Systemic lupus erythematosus patients had significantly worse left ventricular global longitudinal strain compared to healthy controls (-18.56% vs. -19.89%; P=0.028).
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