Key result
A larger baseline VCG-derived T-wave area predicted echocardiographic response to cardiac resynchronization therapy (OR 1.172 per 10 μVs increase, P<0.001), especially in patients with LBBB.
Why the study?
Does a larger baseline T-wave area predict improved echocardiographic response to cardiac resynchronization therapy in chronic heart failure patients?
Population
244 chronic heart failure patients receiving cardiac resynchronization therapy with baseline 12-lead…
Comparison
Larger baseline T-wave area derived from… vs Smaller baseline T-wave area
Design
Cohort
Follow-up
6 months
Authors
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Larger T-wave area may aid CRT response prediction in LBBB; leaves open prospective validation before clinical adoption.
Observational (n=244)
Does a larger baseline T-wave area predict improved echocardiographic response to cardiac resynchronization therapy in chronic heart failure patients?
Odds Ratio: 1.172
p-value: p=<0.001
A larger baseline T-wave area on ECG is an independent predictor of echocardiographic response to CRT in heart failure patients with LBBB.
Engels et al. (2014) conducted an observational in Chronic heart failure with left ventricular conduction delay (n=244). Baseline T-wave area was evaluated on Echocardiographic response (≥5% increase in LV ejection fraction) at 6 months (OR 1.172, p=<0.001). A larger baseline VCG-derived T-wave area predicted echocardiographic response to cardiac resynchronization therapy (OR 1.172 per 10 μVs increase, P<0.001), especially in patients with LBBB.
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