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January 1, 2014International Heart JournalOpen Access

Predictors for Cardiac Resynchronization Therapy Response

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Why the study?

Do optimal left ventricular lead position and LBBB morphology improve response to cardiac resynchronization therapy in patients with heart failure and wide QRS complex?

Population

193 consecutive patients with heart failure and wide QRS complex who successfully underwent cardiac…

Design

Cohort

Follow-up

12 months

Authors

HLHaiyan LinFujian Medical UniversityYZYing ZhouLiaoning University of Traditional Chinese MedicineGXGeng XuGuangdong University of Technology

Discussion

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Overview

Optimal LV lead position may enhance CRT response; leaves open whether non-LBBB independently reduces benefit in randomized settings.

Structured PICO

Do optimal left ventricular lead position and LBBB morphology improve response to cardiac resynchronization therapy in patients with heart failure and wide QRS complex?

P
Population
193 consecutive patients with heart failure and wide QRS complex who successfully underwent cardiac resynchronization therapy (CRT) device implantation
I
Intervention
Cardiac resynchronization therapy (CRT)
O
Outcome
Composite of absolute increase of ≥ 5% in left ventricular ejection fraction (LVEF) compared with baseline at 12 months after CRT implantation without heart failure rehospitalization or any cause of deathcomposite

Optimal left ventricular lead position and LBBB morphology are independent predictors of positive clinical and echocardiographic response to CRT in heart failure patients.

Cite This Study

Lin et al. (2014) studied this question.

synapsesocial.com/papers/6a6fe73bac440176ef288dc4https://doi.org/10.1536/ihj.13-318
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Also Consider

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  1. 1Clinical and electrocardiographic predictors of a positive response to cardiac resynchronization therapy in advanced heart failure2005 · 246 citations
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  4. 4Prediction of response to cardiac resynchronization therapy using simple electrocardiographic and echocardiographic tools2009 · 54 citations
  5. 5Long-term independent predictors of positive response to cardiac resynchronization therapy2012 · 4 citations