February 23, 2005European Heart JournalOpen Access

Clinical and electrocardiographic predictors of a positive response to cardiac resynchronization therapy in advanced heart failure

View Full Paper

Ask AI

Bookmark

Why the study?

What are the clinical and electrocardiographic predictors of a positive response to cardiac resynchronization therapy in patients with advanced heart failure?

Population

139 consecutive patients successfully implanted with a CRT device for refractory congestive heart failure…

Design

Cohort

Follow-up

6 months

Authors

GLGuillaume Lecoq CLChristophe Leclercq ELEmmanuelle Leray

Discussion

Member takes

Overview

DeltaQRS may aid CRT response prediction in advanced HF; hypothesis-generating and requires prospective validation before practice change.

Structured PICO

What are the clinical and electrocardiographic predictors of a positive response to cardiac resynchronization therapy in patients with advanced heart failure?

Population

139 consecutive patients successfully implanted with a CRT device for refractory congestive heart failure, mean age 68+/-9 years, 113 men (81.3%), 69% NYHA class III, 31% NYHA class IV, mean LVEF 21+/-6%, mean QRS duration 188+/-28 ms.

Intervention

Cardiac resynchronization therapy (CRT) with biventricular stimulation

Outcome

Positive response to CRT at 6 months (defined as alive, not re-hospitalized for management of CHF, and NYHA class decreased by 1 point, and/or peak VO2 or 6 min hall-walk increased by >10%)composite

The degree of QRS shortening during biventricular pacing is a strong independent predictor of clinical response to cardiac resynchronization therapy at 6 months.

Cite This Study

Lecoq et al. (2005) studied this question.

synapsesocial.com/papers/6a7dc89a87be3f923b5ca376 https://doi.org/10.1093/eurheartj/ehi146

View Full Paper

Ask AI

Bookmark

February 23, 2005European Heart JournalOpen Access

Clinical and electrocardiographic predictors of a positive response to cardiac resynchronization therapy in advanced heart failure

View Full Paper

Ask AI

Bookmark

Why the study?

What are the clinical and electrocardiographic predictors of a positive response to cardiac resynchronization therapy in patients with advanced heart failure?

Population

139 consecutive patients successfully implanted with a CRT device for refractory congestive heart failure…

Design

Cohort

Follow-up

6 months

Authors

GLGuillaume Lecoq CLChristophe Leclercq ELEmmanuelle Leray

Discussion

Member takes

Overview

DeltaQRS may aid CRT response prediction in advanced HF; hypothesis-generating and requires prospective validation before practice change.

Structured PICO

What are the clinical and electrocardiographic predictors of a positive response to cardiac resynchronization therapy in patients with advanced heart failure?

Population

Intervention

Cardiac resynchronization therapy (CRT) with biventricular stimulation

Outcome

Positive response to CRT at 6 months (defined as alive, not re-hospitalized for management of CHF, and NYHA class decreased by 1 point, and/or peak VO2 or 6 min hall-walk increased by >10%)composite

The degree of QRS shortening during biventricular pacing is a strong independent predictor of clinical response to cardiac resynchronization therapy at 6 months.

Cite This Study

Lecoq et al. (2005) studied this question.

synapsesocial.com/papers/6a7dc89a87be3f923b5ca376 https://doi.org/10.1093/eurheartj/ehi146

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

View Full Paper

Ask AI

Bookmark