Key result
Hypertensive pregnancy was associated with a greater increase in left ventricular mass (92 g vs 28.36 g) and relative wall thickness (0.14 vs 0.03) compared to normotensive pregnancy.
Why the study?
How does cardiac remodeling differ between normotensive pregnancy and pregnancy complicated by hypertension compared to non-pregnant reference states?
Meta-Analysis
How does cardiac remodeling differ between normotensive pregnancy and pregnancy complicated by hypertension compared to non-pregnant reference states?
Absolute Event Rate: 92% vs 28.36%
Hypertensive pregnancy is associated with significantly greater increases in left ventricular mass and relative wall thickness compared to normotensive pregnancy, indicating more pronounced concentric remodeling.
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Suggests hypertensive disorders of pregnancy drive adverse cardiac remodeling; extends the known maternal cardiovascular risk profile while.
Haas et al. (2017) conducted a meta-analysis in Normotensive and hypertensive pregnancy. Hypertensive pregnancy vs. Normotensive pregnancy was evaluated on Change in left ventricular mass (LVM) in grams. Hypertensive pregnancy was associated with a greater increase in left ventricular mass (92 g vs 28.36 g) and relative wall thickness (0.14 vs 0.03) compared to normotensive pregnancy.
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