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February 1, 1986Journal of General Virology

An Epitope Located at the C Terminus of Isolated VP1 of Foot-and-Mouth Disease Virus Type O Induces Neutralizing Activity but Poor Protection

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Authors

RMR. H. MelonenSBS J Barteling

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Overview

Neutralizing activity from VP1 may not predict protection in pigs; leaves open whether conformational epitopes are required for FMDV vaccines.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Melonen et al. (1986) studied this question.

synapsesocial.com/papers/6a6f5643ac440176ef28077fhttps://doi.org/10.1099/0022-1317-67-2-289
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Main Antigenic Determinant Detected by Neutralizing Monoclonal Antibodies on the Intact Foot-and-Mouth Disease Virus Particle is Absent from Isolated VP11983 · 39 citations
  2. 2Nature of the Antibody Response to the Foot-and-Mouth Disease Virus Particle, its 12S Protein Subunit and the Isolated Immunizing Polypeptide VP11982 · 27 citations
  3. 3Comparison of the Antibodies Elicited by the Individual Structural Polypeptides of Foot-and-Mouth Disease and Polio Viruses1979 · 87 citations
  4. 4A Study of the Cross-reacting Antigens on the Intact Foot-and-Mouth Disease Virus and its 12S Subunits with Antisera Against the Structural Proteins1980 · 47 citations
  5. 5Location and Characterization of the Antigenic Portion of the FMDV Immunizing Protein1982 · 367 citations