Key result
Evaluation of local FMD vaccines in cattle sera showed 37.7% positivity for non-structural proteins, highlighting the need for vaccines that differentiate infected from vaccinated animals.
Why the study?
Vaccination is the main approach to control the spread of foot-and-mouth disease in Egypt, motivating an evaluation of governmental and prevailing local vaccines in cattle sera.
Does vaccination with local governmental or prevailing vaccines induce antibodies against FMDV in cattle?
Observational (n=130)
Does vaccination with local governmental or prevailing vaccines induce antibodies against FMDV in cattle?
Locally prepared vaccines induce antibody responses against FMDV serotypes A, O, and SAT2 in cattle, highlighting the need for vaccines that differentiate infected from vaccinated animals.
Local FMD vaccines elicit variable serotype antibodies in Egyptian cattle; leaves open whether program improvements can enhance control in endemic settings.
Vaccination was the main approach to control spreading of FMD disease in Egypt. This study was carried out for evaluation of vaccination by governmental and prevailing local vaccines in cattle sera in menofia governorate during the period from October 2018 to May 2019. A total 130 serum samples were collected to evaluate the antibodies against FMDV. 30 samples were used as control, 50 samples collected from animals received local governmental vaccine and 50 samples from animals received local prevailing vaccine. 49 out of 100 serum samples (37.7%) were positive and 81 out of 130 serum samples (62.3%) were negative for NSP. Results were (0.0), 3(3.7%) pre-vaccination and 27(33.33%), 18(22.22%) 1st MPV- 25(30.86%), 18(22.22%) 2nd MPV-15(18.52%), 13(16.05%) 3rd MPV and (0.0), 9(11.11%) 4th MPV for serotype A. For serotype (O): 9(11.1%), 10(12.4%) pre-vaccination- 36(44.44%), 28(34.56%) 1st MPV-33(40.74%), 27 (33.33%) 2nd MPV-24(29.63%), 20(24.7%) 3rd MPV-14(17.3%), 12(14.80%) 4th MPV. For serotype (SAT2): 4(4.9%), 24(4.93%) pre-vaccination-30 (37.03%), 21(25.93%) 1st MPV-27(33.33%), 21(25.93%) 2nd MPV- 18 (22.22%), 14(17.3%) 3rd MPV-3 (3.71%), 4(4.93%) 4th MPV. In Conclusion. FMD controlling requires vaccines that will supply disparity of infected from vaccinated animals.
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Shaban et al. (2021) conducted an observational in Foot and mouth disease (FMD) (n=130). Local governmental and prevailing local vaccines vs. Unvaccinated control was evaluated on Antibodies against FMDV (NSP). Evaluation of local FMD vaccines in cattle sera showed 37.7% positivity for non-structural proteins, highlighting the need for vaccines that differentiate infected from vaccinated animals.
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