Why the study?
Does multiple intradermal tongue inoculation improve the detection of foot-and-mouth disease virus compared to subcutaneous inoculation in cattle?
Population
Cattle (for testing non-infectivity of foot-and-mouth disease vaccines)
Comparison
Multiple intradermal tongue inoculation vs Subcutaneous inoculation
Design
Preclinical
Authors
Loading...
Multiple intradermal tongue inoculation may improve FMDV detection sensitivity in cattle; leaves open its routine use for vaccine safety testing pending validation.
Does multiple intradermal tongue inoculation improve the detection of foot-and-mouth disease virus compared to subcutaneous inoculation in cattle?
Multiple intradermal tongue inoculation is statistically and methodologically superior to subcutaneous inoculation for testing the non-infectivity of foot-and-mouth disease vaccines in cattle.
W. M. Henderson (1952) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: