Key result
Cisplatin and bleomycin-containing chemotherapy was associated with the development of acute peripheral arterial thrombosis and superficial femoral artery occlusion requiring amputation in a 58-year-old man.
Population
1 adult male with mixed germ cell neoplasm and cardiovascular risk factors.
Design
Case_report
Follow-up
During 4 cycles of chemotherapy
Authors
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May indicate rare arterial thrombosis risk during cisplatin-bleomycin therapy; hypothesis-generating case requiring confirmation.
Case Report (n=1)
Cisplatin and bleomycin-containing chemotherapy can cause severe acute peripheral vascular toxicity, highlighting the need for cardiovascular evaluation and potential prophylactic anticoagulation in high-risk patients.
Ozkan et al. (2016) conducted a case report in Testicular cancer (n=1). Cisplatin and bleomycin-containing chemotherapy (BEP) was evaluated on Acute peripheral arterial thrombosis. Cisplatin and bleomycin-containing chemotherapy was associated with the development of acute peripheral arterial thrombosis and superficial femoral artery occlusion requiring amputation in a 58-year-old man.
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