Key result
PVB chemotherapy links to acute vascular ischemic events, including angina in ~38% of patients.
Why the study?
Does combination chemotherapy with cisplatin, vinblastine, and bleomycin cause acute vascular ischaemic events in patients with testicular cancer?
Population
21 consecutive patients with testicular cancer
Design
Case_series
Follow-up
during chemotherapy
Authors
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May warrant vigilance for ischemic events during PVB chemotherapy; leaves open need for prospective studies to guide monitoring or regimen changes.
Observational (n=21)
Does combination chemotherapy with cisplatin, vinblastine, and bleomycin cause acute vascular ischaemic events in patients with testicular cancer?
Combination chemotherapy with cisplatin, vinblastine, and bleomycin for testicular cancer is associated with a high frequency of acute vascular ischemic events, including angina and Raynaud's phenomenon.
Stefenelli et al. (1988) conducted an observational in Testicular cancer (n=21). Bleomycin, vinblastine, and cisplatin (PVB) chemotherapy was evaluated on Acute vascular ischaemic events. Combination chemotherapy with bleomycin, vinblastine, and cisplatin (PVB) for testicular cancer frequently caused acute vascular ischemic events, including angina pectoris in 38% of patients.
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