Key result
A single-day ambulatory ECG monitoring PVC count differed by 69% from the mean daily count derived from a 25-30 day recording.
Why the study?
PVCs are generally quantified using 24h ECG recordings, but the diagnostic accuracy, day-to-day variability, and optimal monitoring duration are unknown.
Does extended ambulatory ECG monitoring improve diagnostic accuracy of PVC quantification in patients with frequent PVCs?
Observational (n=1,376)
Does extended ambulatory ECG monitoring improve diagnostic accuracy of PVC quantification in patients with frequent PVCs?
Extended ambulatory ECG monitoring reveals high day-to-day variability in PVC frequency, suggesting that standard 24-hour recordings may be highly inaccurate for quantifying PVC burden.
24h ECGs risk misclassifying PVC burden due to variability; leaves optimal duration open for prospective studies.
Background Premature ventricular complexes (PVCs) are generally quantified using a 24h ECG recording, but the diagnostic accuracy is unknown. We aimed to determine the day-to-day variability and optimal monitoring duration for PVC measurements among patients with frequent PVCs. Methods We included all patients who underwent a clinical ambulatory ECG recording lasting 25-30 days, using the PocketECG device (Medi-Lynx, USA) during 2017, who did not have atrial fibrillation, and in whom ≥1000 PVCs were registered during one of the monitored days. All arrhythmias were manually verified. PVC variability was calculated as the percentage of the mean daily PVC count after full recording. Results The study population consisted of 1,376 individuals (median age 76.0 years, 53% men). Figure 1a shows the population distribution of the mean daily PVC counts. The mean daily PVC count was 2780 (standard deviation: 1556, range 0 - 56,262). A single-day PVC count differed by 69% from the mean daily count. After 18 days the obtained mean PVC count differed
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Johnson et al. (2021) conducted an observational in Frequent premature ventricular complexes (n=1,376). Ambulatory ECG monitoring was evaluated on PVC variability (percentage of the mean daily PVC count after full recording). A single-day ambulatory ECG monitoring PVC count differed by 69% from the mean daily count derived from a 25-30 day recording.
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