Population
Mice, dogs, and cats (experimental poliomyelitis models)
Comparison
Poliomyelitis virus infection vs Normal (uninfected) brain/tissue
Design
Preclinical
Authors
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Should not change poliomyelitis management; hypothesis-generating for reversible neuronal injury in viral models.
Experimental poliomyelitis infection decreases anaerobic glycolysis in the brain without significantly changing oxygen utilization, suggesting reversible injury to nerve cells.
Racker et al. (1942) studied this question.
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