Why the study?
Does poliomyelitic infection cause electrophysiologic alterations of the brain in animal models and humans?
Population
7 rhesus monkeys, 10 guinea pigs, and 17 persons with postpoliomyelitic paralyses
Comparison
Experimental infection with simian or murine… vs Control injection
Design
Preclinical
Authors
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EEG changes in poliomyelitis remain hypothesis-generating from animal and early human data; leaves open need for modern validation.
Does poliomyelitic infection cause electrophysiologic alterations of the brain in animal models and humans?
This study investigated electroencephalographic changes during poliomyelitis infection in animal models and humans with postpoliomyelitic paralyses.
Bernard L. Pacella (1947) studied this question.
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