Key result
Intracerebral injection of poliomyelitis virus in Macacus rhesus monkeys does not produce immediate specific histologic changes, though transfer experiments can detect the virus.
The study demonstrates that poliomyelitis virus can be present and spread in the central nervous system of monkeys before histologic changes are evident.
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Does not support early histologic diagnosis of poliomyelitis; leaves open questions on viral detection timing before tissue changes in primate models.
John A. Toomey (1937) studied Poliomyelitis. Intracerebral injection of poliomyelitis virus was evaluated on Histologic evidence of virus presence. Intracerebral injection of poliomyelitis virus in Macacus rhesus monkeys does not produce immediate specific histologic changes, though transfer experiments can detect the virus.
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