Key result
Blocking the nasal olfactory area with 1% zinc sulfate does not prevent the production of poliomyelitis when the virus is injected intravenously in monkeys.
Why the study?
Does blocking olfactory nerve connections prevent the acquisition of poliomyelitis following intravenous injection of the virus in Macacus rhesus monkeys?
Does blocking olfactory nerve connections prevent the acquisition of poliomyelitis following intravenous injection of the virus in Macacus rhesus monkeys?
Blocking the nasal olfactory area does not prevent the production of poliomyelitis when the virus is injected intravenously in monkeys.
Answers are grounded in this paper and cite their sources.
Indicates olfactory routes are dispensable for intravenous poliomyelitis in monkeys; hypothesis-generating for viral entry but should not inform human practice.
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John A. Toomey (1939) studied Poliomyelitis. Intravenous injection of poliomyelitis virus after blocking nasal olfactory area with 1% zinc sulfate was evaluated on Acquisition of poliomyelitis. Blocking the nasal olfactory area with 1% zinc sulfate does not prevent the production of poliomyelitis when the virus is injected intravenously in monkeys.
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