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Contaminants rather than oleic acid itself may cause chick pericardial edema; leaves open the toxin's identity and relevance to human or research use.
Summary A number of samples of commercially‐prepared (U.S.P.) oleic acids and glycerol esters of oleic acids were shown to contain a material which produces pericardial edema in chicks. The active material was concentrated from either the oleic acid or the glycerol mono‐ester by molecular distillation. Four of the 11 samples of oleic acid were inactive; this indicates that the pericardial edema is not caused by the fatty acid itself but by an incidental material in the fatty acid.
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Ames et al. (1960) studied this question.
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